Something wicked this way comes with the fourth season of “True Blood,” which premiered on HBO last night. In the season opener, Sookie Stackhouse (Anna Paquin) ventured from Bon Temps to meet her, um, fairy godmother, and it looks like she may be pursuing a romance with Eric, according to costar Stephen Moyer. (Watch a preview above.)

 But an equally intriguing storyline has Lafayette (Nelsan Ellis) flirting with his witch-like characteristics. Season 4, based loosely on Charlaine Harris’ soapy novel “Dead to the World,” brings more witches into the mix, and Sunday's premiere had Lafayette being persuaded by hunky boyfriend Jesus (Kevin Alejandro) to join a coven.

The Cheat Sheet: 'True Blood' Season 4

“I’d say the witches certainly pose the greatest threat to the vampires that we’ve seen yet,” executive producer Alexander Woo told the Hollywood Reporter.

The coven of witches is led by Marnie (Fiona Shaw of the “Harry Potter” films), a witch whose plans could foil the entire vampire establishment when she goes head to head with the bloodsuckers. Alexandra Breckenridge (“Dirt,” “Family Guy”) takes on the role of Katerina, one of Marnie’s followers.

Shaw has signed on as a season regular, so we can expect to see quite a bit more of her storyline. The all-powerful witch pretty much goes after anyone who crosses her.

“I think what [the witches] represent is the power of the human spirit and sort of the power of life,” Woo added. “And they use that to perform their magic. Whereas vampires are the dead. They represent death, and it’s the contrast of life versus death with human versus vampire that I think is the crux of this season. And the very thing that allows the vampires to be animated is the thing that the witches can control.”

"True Blood" isn't the only upcoming programming bringing wiccan warriors back to the tube. Here's a look at some of the small-screen’s most memorable witches and a look forward to those who will join their TV coven.